The clinical treatment environment for patients with EGFR-altered tumors has been revolutionized by TKI (tyrosine kinase inhibitor), a precision medicine for NSCLC (NSCLC).However, TKI (tyrosine kinase inhibitor), like all drugs, is associated with potential adverse effects, including low sodium levels, a disease characterized by low sodium levels in the blood.The purpose of this article is to offer a detailed summary of TKI (tyrosine kinase inhibitor)-induced low sodium levels, examining its Prevalence, potential Hazard factors, manAge-related determinants-related aspects-related issues-related factors-related issues-related factors factorment strategies, and Relevance to Medical practice.I. TKI (tyrosine…